https://nova.newcastle.edu.au/vital/access/ /manager/Index ${session.getAttribute("locale")} 5 A methanol and protic ionic liquid Ugi multicomponent reaction path to cytotoxic a-phenylacetamido amides https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:44078 6] and the protic ionic liquid ethanolammonium nitrate (ETAN) failed. Microwave irradiation in EAN facilitated rapid access to three focused libraries, based on the parent isocyanide: cyclohexyl isocyanide, benzyl isocyanide and ethyl isocyanoacetate. Analysis of the structure activity relationship data suggested the presence of a bulky moiety originating from the isocyanide (cyclohexyl and benzyl) enhanced cytotoxicity. Removal of the acetylenic H-atom from the ethanoic acid moiety was detrimental to cytotoxicity. The most active analogues produced, N-(2-cyclohexylamino)-1-(4-methoxyphenyl)-2-oxoethyl-N-(3,5-dimethoxyphenyl)propiolamide, returned average GI50 values of ≤1 μM across the cancer cell lines evaluated. Combined, these data suggest that analogues of this nature are interesting potential anti-cancer development leads.]]> Wed 26 Oct 2022 10:31:27 AEDT ]]> The development of flow chemistry methodologies for the synthesis of potential anti-cancer agents https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:21973 Wed 11 Apr 2018 15:31:36 AEST ]]> A novel process concept for the capture of CO₂ and SO₂ using a single solvent and column https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18539 Wed 11 Apr 2018 14:38:57 AEST ]]> Acetic acid on silicon (001): an exercise in chemical analogy https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17751 Wed 11 Apr 2018 13:47:33 AEST ]]> Investigation of the photochemistry of the poly{p-phenylenevinylene} precursor system: Implications for nanolithography https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:3337 Wed 11 Apr 2018 13:01:56 AEST ]]> Facile amidinations of 2-aminophenylboronic acid promoted by boronate ester formation https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:48151 Wed 08 Mar 2023 14:43:43 AEDT ]]> A lower bound on the number of perfect matchings in benzenoid systems https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:46304 Tue 15 Nov 2022 10:07:48 AEDT ]]> The short-term reduction of uranium by nanoscale zero-valent iron (nZVI): role of oxide shell, reduction mechanism and the formation of U(v)-carbonate phases https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:32238 VI) with fresh, (anoxic) aged and corroded nZVI particles was investigated under aqueous conditions conducive to the formation of thermodynamically stable U(VI)-Ca-CO₃ ternary aqueous complexes. The first stage of the reaction between U(VI) and nZVI was assigned to sorption processes with the formation of surface U(VI)-carbonate complexes. Aged nZVI removed U(VI) faster than either fresh or corroded nZVI and it is hypothesized that U reduction initially occurs through the transfer of one electron from Fe(II) in the nZVI surface oxide layer. Evidence for reduction to U(V) was obtained through X-ray photoelectron spectroscopy and by determination of U-O bond distances of ~2.05 and 2.27 Å, using U LIII -edge X-ray absorption spectroscopy, which are similar to those observed for the U(v) site in the mixed U(v)/U(VI) carbonate mineral wyartite. Scanning transmission electron microscopy also demonstrated that U was present as a nanoparticulate phase after one day of reaction, rather than a surface complex. Further reduction to U(IV), as observed in previous studies, would appear to be rate-limiting and coincident with the transformation of this meta-stable U-carbonate phase to uraninite (UO).]]> Tue 15 May 2018 16:00:13 AEST ]]> Printing of PEDOT:PSS for top gate organic thin film transistor https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:43887 Tue 04 Oct 2022 13:52:34 AEDT ]]> Structure and energetics of hydrogenated and dehydrogenated carbon tori https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:457 Thu 25 Jul 2013 09:09:50 AEST ]]> Calculation and meaning of feasible band boundaries in multivariate curve resolution of a two-component system https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:7368 Sat 24 Mar 2018 08:40:14 AEDT ]]> An SO2 tolerant process for CO2 capture https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18737 Sat 24 Mar 2018 08:02:48 AEDT ]]> [1.1.1]Cryptand: directions for its use as a variable-pH kinetic molecular device https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18035 Sat 24 Mar 2018 07:56:31 AEDT ]]> Anti-malarial, anti-algal, anti-tubercular, anti-bacterial, anti-photosynthetic, and anti-fouling activity of diterpene and diterpene isonitriles from the tropical marine sponge Cymbastela hooperi https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:17945 Sat 24 Mar 2018 07:56:29 AEDT ]]> Crystallisation kinetics in thin films of dihexyl-terthiophene: the appearance of polymorphic phases https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18010 Sat 24 Mar 2018 07:56:17 AEDT ]]> Combined friction force microscopy and quantum chemical investigation of the tribotronic response at the propylammonium nitrate–graphite interface https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20325 Sat 24 Mar 2018 07:55:10 AEDT ]]> Water-based nanoparticulate solar cells using a diketopyrrolopyrrole donor polymer https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:18538 Sat 24 Mar 2018 07:50:11 AEDT ]]> Porphyrin complexes containing coordinated BOB groups: synthesis, chemical reactivity and the structure of [BOB(tpClpp)]²⁺ https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:5225 Sat 24 Mar 2018 07:44:21 AEDT ]]> Regioselective N- and C2-electrophilic substitution of 3-substituted indoles (short communication) https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:366 Sat 24 Mar 2018 07:42:37 AEDT ]]> The effect of ionic liquid hydrophobicity and solvent miscibility on pluronic amphiphile self-assembly https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:28594 Sat 24 Mar 2018 07:37:28 AEDT ]]> Interaction between two moving jets in immiscible liquid-liquid systems: An experimental study https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:25536 Sat 24 Mar 2018 07:26:03 AEDT ]]> Localization of a bound particle outside the potential well https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:3283 Sat 24 Mar 2018 07:22:22 AEDT ]]> Quantum chemical investigation of the growth and chemistry of graphene https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:33900 Mon 23 Sep 2019 13:35:32 AEST ]]> A novel geopolymer route to porous carbon: high CO2 adsorption capacity https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:45447 Fri 28 Oct 2022 14:08:10 AEDT ]]> Structure and nanostructure in ionic liquids https://nova.newcastle.edu.au/vital/access/ /manager/Repository/uon:20324 Fri 28 Aug 2015 14:20:28 AEST ]]>